Professor, Neurology and Neuroscience
Director, N. Bud Grossman Center for Memory Research and Care
Edmund Wallace and Anne Marie Tulloch Chairs in Neurology and Neuroscience
Brain sciences, Alzheimer’s disease
Karen Hsiao Ashe is a leader in the field of Alzheimer’s research. She has demonstrated that, long before brain cells die, an abnormal form of a normal brain protein disrupts cognitive function. This abnormal protein may be the agent that initiates Alzheimer’s disease. Ashe also has created transgenic mice modeling Alzheimer’s disease that are among the most commonly used models in the world. Her findings have broad implications for the early diagnosis, prevention, and treatment of Alzheimer’s disease.
Sources of Funding
National Institutes of Health
Minnesota Partnership for Biotechnology and Medical Genomics